Sensitive cell cultures
Complex cell models like 2D stem cells and 3D organoids are essential in modern drug discovery.
advancing sensitive cell cultures.
High variability
Yet, their sensitivity makes handling difficult, limits automation and results in variable, operator-dependent workflows which limits their use.
Gentle, fluidic automation
Our technology gently automates medium exchange -without disrupting the culture - empowering researchers to unlock the full potential of their complex cell cultures.
gentle medium exchange with maximum cell retention.
Sync’s gentle and reproducible medium refreshment outperforms manual pipetting in adherent and suspension sensitive cell cultures.
Adherent cells were refreshed 1× or 6× every 30 minutes. The suspension cells were refreshed once reaching full or partial medium change.
Kinetics
Drug, nutrient, and hormone levels fluctuate constantly in the human body.
The challenge
Conventional in vitro tests use static exposure, missing real-life kinetics.
Our solution
We enable time-controlled concentration changes - bringing pharmacokinetics into in vitro models.
bringing pharmacokinetics to standard well plates.
With Sync’s technology, drug exposure profiles can be precisely controlled—in your current workflow.
In a chemotherapeutic study, two distinct kinetic profiles led to different levels of cell death, underscoring the importance of kinetic drug testing for accurate toxicity prediction.
Consistent results across replicates highlight the precision and reliability of our system.
Plug & play
Seamlessly integrates with your standard 96-well plates—no special hardware or workflows needed.
Gentle by design
Automated medium exchange without disrupting cells - no shear stress, no loss.
Kinetics
Our automated dose- and mixing unit can provide different compound concentrations at any given time.
Service applications
Pharmacokinetics? Changing glucose levels? We can help you to answer kinetics questions in vitro.
Service readouts
We can track your cells over time using (fluorescent) imaging. Or your preferred downstream assays.
Coming soon: Product
We are working on a product to bring Sync’s technology to your lab. Contact us for more info.
we are engineers and biologists who make solutions that simply work.
ir. Berend van Meer, PhD
Managing Director
Tessa de Korte
Director of Biology
ir. Jasmijn Büskens
System Engineer
ir. Marije Bol
jr. System Engineer
Melissa Zuiderwijk
Research Technician
Bram Meijlink, PHD
Application Scientist
Clara Ferrer Castellà
Data Scientist
